Women habitual miscarriage alert to these male factors!

It is often habitual to think that miscarriage is the cause of a woman. It is true that a woman’s activities, a woman’s physical condition, a woman’s history of illness, etc. can all contribute to the appearance of miscarriage.

 

But! In many cases, men are often to blame in miscarriages too!

 

Since sperm also plays an important role in the conception process, the health of the man, and the quality of his sperm, also directly affects the health of the fetus. Especially for older men, it is necessary to pay more attention to physical examination, otherwise it is very easy to lead to habitual abortion.

For couples whose wives have repeated miscarriages, it is necessary to conduct a comprehensive physical examination of the male. The male chromosomal factor, sperm factor and autoimmune factor are all crucial to conception, and it should not be assumed that the male has nothing to do with the woman’s pregnancy. Male factors have an important impact on fetal congenital abnormalities and habitual abortions.

 

 

What are the factors that need to be taken care of in males for habitual abortion?

 

1. Male chromosomes

 

Abnormal chromosome structure or number abnormalities (e.g. 45, X or 47, XXY) are associated with low pregnancy rates and increased miscarriage rates. Most of these men have significant low fertility or infertility as well as resulting in high miscarriage rates of 50% or more.

 

2. Sperm quality

 

Sperm motility and quality are important factors that may affect conception and miscarriage rates. Most of the studies on the association of sperm quality with habitual abortion and miscarriage rates have been done with reference to standard semen analysis parameters and have found a correlation between sperm quality and early miscarriage and fetal death.

 

3. Male age

 

Fertility decreases progressively with age in adult men. In older men, progressive testicular tissue atrophy, reduced daily sperm production, and morphological changes in testicular reproductive tissues may occur, resulting in lower sperm quality, lower conception rates, increased miscarriage rates, and increased fetal mortality. The increased risk of miscarriage depends on the age of both parents.

 

The risk of miscarriage is increasing in men aged 40 years and older, especially when the mother is 35 years or older. Studies have shown that paternal age over 50 years of age alone affects early fetal mortality twice as much as paternal age of 45 years.

Miscarriage, and men also have a relationship

 

1. embryo, placenta-related influences

 

There is evidence that paternal chromosomes affect early embryonic development and that their expressed genes may affect placental quality. The integrity of the sperm is most important for sperm-egg interaction, fertilization and early embryonic development.

 

2. Extrinsic factors

 

Male spermatogenesis is ongoing, so adult male sperm are particularly likely to undergo mutations that do not manifest themselves in somatic cells, and external exposures can affect sperm as a result.

 

Ionizing radiation, air pollution, and other environmental exposures have an effect on inducing mutations or sperm aneuploidy. Treatment for cancer can increase the mutation rate of sperm DNA.

 

Men are more likely to have mutations as they age, which can affect sperm DNA, decrease conception, increase miscarriage rates and increase birth defects.

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